As industries continue to understand Industry 4.0 – the potential of IIoT is yet to be realised. The need to develop efficient systems comes with its own set of unique challenges. Apart from work culture transformation and regulatory challenges, enterprises are faced with multi-dimensional challenges; primarily, communication and collaboration across systems. How can industries cross this hurdle and adopt Industrial IoT solutions smoothly? Introducing OPC UA – a complete solution that covers security, data preservation across layers, data analytics of meta-data and vendor-platform independence. The system looks at a global communication standard that takes care of complex communication channels between central components. This white paper aims to address interoperability challenges through OPC UA implementation.